Clinical Metabolomics

Our first module focuses on the metabolome, the comprehensive set of metabolites in a biological system, because it fully represents the system’s present state: what-has-happened and what-is-happening. The metabolome lays bare the integration of the organism’s genome and how its expression has been influenced by environmental inputs up to the moment of analysis.

Other -omics are less clinically useful:

  • The genome tells us what-can-happen
  • The transcriptome tells us what-appears-to-be-happening
  • The proteome tells us what-makes-it-happen

Clinical metabolomics encompasses the practical application of the metabolome: the detection of metabolic imbalances and the indicated therapeutic interventions.